CHARACTERIZATION OF RETENTION BEHAVIOR IN SUPERCRITICAL FLUID CHROMATOGRAPHY

Supercritical Fluid Extraction+supercritical Fluid Chromatography

high pressures also requires special equipment. In summary, both RESS crystallization and SAS crystallization appear to be promising methods for generating supersaturation and therefore represent alternatives to conventional crystallization. Such alternatives may prove attractive in applications such as polymer and pharmaceutical processing, or in particle design for drug delivery. It is possib...

Temperature and pressure effects on solubility in supercritical carbon dioxide and retention in supercritical fluid chromatography

Solubilities of some polycyclic aromatic hydrocarbons (PAHs) in supercritical carbon dioxide were measured with a procedure based on a direct on-line combination of a saturation cell to a flame ionization detector. Acenaphthene, anthrance and chrysene were selected as the test solutes. A method was developed and evaluated which enables the measurement of the contribution of solute vapor pressur...

Supercritical Fluid Chromatography

(1995) Journal of Chromatography A 691: 239}246. [43] LeBelle M, Pike RK, Graham SJ, Ormsby ED and Bogard H (1996) Journal of Pharmaceutical and Biomedical Analysis 14: 793}800. [44] Bernal JL, del Nozal MJ, Martin MT and Diez-Masa JC and Cifuentes (1998) Journal of Chromatography A 823: 423}431. [45] Polettini A, Bouland GM and Montagna M (1998) Journal of Chromatography B: Biomedical Sciences...

Supercritical Fluid Chromatography

Since there is an enormous volume of information on the separation of antibiotics in the literature, readers should be able to Rnd HPLC conditions for almost any antibiotic of interest. Readers are also encouraged to consult the ofRcial compendia for analysis of bulk or formulated drugs. For analysis of biological samples, the samples may be directly injected with a column switching technique i...

Supercritical Fluid Chromatography